11 research outputs found

    Introduction to fMRI: experimental design and data analysis

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    This provides an introduction to functional MRI, experimental design and data analysis procedures using statistical parametric mapping approach

    Emotive stimuli-triggered participant-based clustering using a novel split-and-merge algorithm

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    by Surabhi S. Nath, Dyutiman Mukhopadhyay and Krishna P Miyapura

    BOLD responses in reward regions to hypothetical and imaginary monetary rewards

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    Monetary rewards are uniquely human. Because money is easy to quantify and present visually, it is the reward of choice for most fMRI studies, even though it cannot be handed over to participants inside the scanner. A typical fMRI study requires hundreds of trials and thus small amounts of monetary rewards per trial (e.g. 5p) if all trials are to be treated equally. However, small payoffs can have detrimental effects on performance due to their limited buying power. Hypothetical monetary rewards can overcome the limitations of smaller monetary rewards but it is less well known whether predictors of hypothetical rewards activate reward regions. In two experiments, visual stimuli were associated with hypothetical monetary rewards. In Experiment 1, we used stimuli predicting either visually presented or imagined hypothetical monetary rewards, together with non-rewarding control pictures. Activations to reward predictive stimuli occurred in reward regions, namely the medial orbitofrontal cortex and midbrain. In Experiment 2, we parametrically varied the amount of visually presented hypothetical monetary reward keeping constant the amount of actually received reward. Graded activation in midbrain was observed to stimuli predicting increasing hypothetical rewards. The results demonstrate the efficacy of using hypothetical monetary rewards in fMRI studies

    Neuroinformatics Tools for Functional MRI: Experimental Design and Data Analysis

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    Neuroimaging in vivo is becoming popular from the last two decades. The primary quest of neuroimaging is to better-understanding the functions of various brain areas pertaining to various cognitive processes of interest. Though there are several neuroimaging techniques available currently, the functional Magnetic Resonance Imaging (fMRI) is playing an important role in the field of Imaging Neuroscience. In this paper an introduction to fMRI, the issues related to experimental design and analysis will be presented. This paper also discusses some of the neuroinformatics tools available for fMRI research

    Music identification using brain responses to initial snippets

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    Naturalistic music typically contains repetitive musical patterns that are present throughout the song. These patterns form a signature, enabling effortless song recognition. We investigate whether neural responses corresponding to these repetitive patterns also serve as a signature, enabling recognition of later song segments on learning initial segments. We examine EEG encoding of naturalistic musical patterns employing the NMED-T and MUSIN-G datasets. Experiments reveal that (a) training machine learning classifiers on the initial 20s song segment enables accurate prediction of the song from the remaining segments; (b) β and γ band power spectra achieve optimal song classification, and (c) listener-specific EEG responses are observed for the same stimulus, characterizing individual differences in music perception.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Design Aesthetic
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